注射用磷酸肌酸钠对经尿道前列腺电切手术病人术毕动脉血气的影响

摘要

目的观察注射用磷酸肌酸钠对经尿道前列腺电切手术(TURP)病人术毕血气的影响.方法80例行TURP手术病人，随机分为磷酸肌酸钠组(P组)和对照生理盐水组(S组)，每组40例，实验组静脉给予磷酸肌酸钠2g(用生理盐水100ml溶解)，对照组给予生理盐水100ml.观察记录术前和术毕血红蛋白(Hb)、血液PH值、动脉血氧分压(PaO2)和碱剩余(BE).结果两组病人术毕的Hb较术前均出现了明显的下降(P<0.05)，而在S组，术毕的PH和P aO2均较P组低(P<0.05).结论注射用磷酸肌酸钠能有效的防治TURP病人术毕PH值的下降，提高PaO2.%Objective: To observe the effect of creatine phosphate sodium on postoperative arterial blood gas of patients undergoing transurethral prostatic resection. Methods:50 patients undergoing transurethral prostatic resection were randomly divided into creatine phosphate sodium (P group )(n=25) and physiological saline (S) group (n=25).The trial group was administered creatine phosphate sodium (2g, soluted by 100ml N.S.),and the control group was administered 100ml physiological saline. To record preoperative and postoperative Hemoglobin value ( Hb ), blood PH value ( PH ), arterial partial pressure of oxygen ( PaO2) and base excess ( BE ). Results: The HB values of the two groups were significantly lower postoperatively comparing with preoperative levels ( P<0.05),the postoperative PH and PaO2 in group S was lower than that in group P( P<0.05). Conclusions: Creatine phosphate sodium can effectively prevent the postoperative decrease of PH and increase PaO2 of patients undergoing transurethral prostatic resection.