阻断法气道阻力测定在儿童支气管哮喘诊疗中的应用

摘要

Objective:Through the comparision of the change of the index of pulmonary airway resistance and pulmonary ventilation function in children with bronchial asthma before and after the standardized treatment,to investigate the changes of the two tests,to clear correlations between determination of airway resistance blocking technology(Rint) and pulmonary ventilation function.Methods:50 cases of children with asthma were selected,using the pulmonary function test system,pulmonary airway resistance and pulmonary ventilation function were measured in the acute attack of asthma and remission stage after formal treatment.We compared the measured and predicted values of each period.Results:In acute attack period of children with asthma, the measured values of the lung airway resistance and pulmonary ventilation function were significantly higher than the predicted value,in remission,pulmonary airway resistance index was normal or nearly normal.The response of single block method for the determination of pulmonary airway resistance and pulmonary function was consistent.Conclusion:In children with asthma, pulmonary airway resistance had specific and dynamic changes in the acute stage and remission stage,the response of single block method Raw for the determination of pulmonary airway resistance and pulmonary function was consistent,lung airway resistance detection had a good effect on the diagnosis of asthma in young children,to judge the curative effect and the condition.This study clarified the relationship between childhood asthma and pulmonary airway resistance through dynamic analysis of the changes of the expected value and the measured value of pulmonary airway resistance and pulmonary ventilation function in children with bronchial asthma.%目的：通过对比支气管哮喘患儿规范化治疗前后肺气道阻力和常规肺通气功能指标的变化，探讨2项检查改变的情况，明确阻断技术测定气道阻力(Rint)和常规肺通气功能的相关性。方法：收治哮喘患儿50例，采用肺功能测定系统分别于哮喘急性发作期、正规治疗后缓解期行肺气道阻力和常规肺通气功能测定，比较各期实测值与预测值。结果：哮喘患儿急性发作期肺气道阻力和常规肺通气功能实测值均较预测值明显升高，缓解期肺气道阻力指标恢复正常或接近正常。单阻断法测定肺气道阻力与常规肺功能对气道状况的反应是一致的。结论：哮喘患儿的肺气道阻力在急性期和缓解期存在特异性动态变化，单阻断法测定Raw与常规肺功能对气道状况的反应是一致的，肺气道阻力检测在低龄儿童哮喘的诊断、疗效及病情判断方面具有良好的作用。本研究通过动态分析哮喘患儿肺气道阻力和常规肺通气功能检测预计值和实测值的变化，明确儿童哮喘与肺气道阻力的关系。