角膜基质内注射氟康唑治疗真菌性角膜炎的疗效分析

摘要

目的：探讨角膜基质内注射氟康唑治疗真菌性角膜炎的临床价值。方法：2013年10月-2014年10月收治真菌性角膜炎患者57例，对所有患者给予角膜基质内注射氟康唑治疗，分析其治疗效果。结果：本组57例患者中，治愈42例(73.68%)，好转13例(22.81%)，无效2例(3.51%)，临床治疗总有效率96.49%。无一例患者出现角膜切口感染。注射以后没有明显刺激症状和疼痛，无一例患者出现角膜内皮失代偿。临床住院时间6～30 d，平均(14.2±6.8)d。结论：真菌性角膜炎采取角膜基质内注射氟康唑治疗，可以有效促进溃疡愈合，使住院时间明显缩短，具有临床推广价值。%Objective:To investigate the application value of fluconazol injection in coneal stroma in the treatment of fungal keratitis.Methods:57 patients with fungal keratitis were selected from October 2013 to October 2014.All the patients were given fluconazol injection in coneal stroma,and analyzed the therapeutic effect.Results:In 57 patients in this study,there 42 cases were cured(73.68%);13 cases were improved(22.81%);2 cases were invalid(3.51%),the total efficiency was 96.49%.There was none case occured corneal incision infection.Without obviously irritation and pain after the injection,and also had none of the patients with corneal endothelial decompensation.The hospitalization time was 6~30 days,and averaged(14.2 ± 6.8) days.Conclusion:Fluconazol injection in coneal stroma use in fungal keratitis can promote the healing of ulcer effectively,and shorten the hospitalization time obviously,so it has value to be spread in clinical.