慢性丙型肝炎发展至肝硬化的临床危险因素分析

摘要

目的：研究慢性丙型肝炎(CHC)发展至肝硬化(LC)的临床危险因素。方法：选取慢性丙型肝炎感染患者85例，根据影像学结果分为CHC患者50例、LC患者35例，对CHC发展至LC的各种可能影响因素进行回顾性分析。结果：慢性HCV感染者感染途径、长期饮酒、AST水平、糖尿病、脂肪肝、未行抗病毒治疗成为HCV感染至肝硬化、肝癌的危险因素。结论：HCV感染发展至肝硬化、肝癌受感染途径、长期饮酒、AST水平、糖尿病、脂肪肝、未抗病毒治疗等因素影响，与HCV-RNA水平、ALT水平关系不明显。%Objective:To study the clinical risk factors of chronic hepatitis c(CHC) to cirrhosis(LC).Methods:85 patients with chronic hepatitis c infection were selected.According to the imaging results,they were divided into CHC patients in 50 cases and LC patients in 35 cases.All possible influence factors of CHC to LC were retrospectively analyzed.Results:The infection route, long-term drinking,AST level,diabetes,fatty liver,no antiviral of patients with chronic HCV infection were the risk factors of HCV infection to cirrhosis and liver cancer.Conclusion:HCV infection to cirrhosis and liver cancer is influenced by the infection route, long-term drinking,AST level,diabetes,fatty liver,no antiviral treatment and other factors,the correlation with HCV-RNA level, ALT level are not obvious.