幽门螺杆菌感染与门静脉高压性胃病的临床分析

摘要

Objective:To explore the clinical significance between helicobacter pylori(Hp)infection and portal hypertensive gastropathy(PHG).Methods:The patients with liver cirrhosis were given gastroscope rapid urease test,14C or 13C urea breathing test to test Hp.150 patients with chronic gastritis received gastroscopy at the same time were randomly selected as the control.Results:Research shows that Hp positive rate 37% (37/100) of portal hypertensive gastropathy group was significantly lower than Hp positive rate 64.7%(97/150) of the control group,and the differences in gender and age groups had no statistical significance(P>0.05).The difference of Hp infection in portal hypertensive gastropathy had no statistical significance(P>0.05).Conclusion:There is no significant correlation difference between Hp infection and portal hypertensive gastropathy.Hp infection does not play a major role in its pathogenesis. Hp infection is not the main pathogenic factor of liver cirrhosis caused PHG.The PHG patients with Hp infection is no given the conventional anti Hp eradication therapy.%目的：探讨幽门螺杆菌(Hp)感染与门静脉高压性胃病(PHG)之间的临床意义。方法：对肝硬化患者行胃镜快速尿素酶试验、14C或13C尿素呼气试验测Hp。随机选择同期接受胃镜检查为慢性胃炎患者150例作为对照。结果：研究表明门静脉高压性胃病组Hp阳性率37%(37/100)明显低于对照组Hp阳性率64.7%(97/150)，且在性别和年龄间差异均无统计学意义(P＞0.05)；Hp感染在两组的差异无统计学意义(P＞0.05)。结论：Hp感染与门静脉高压性胃病无统计学相关性差异，Hp感染在其发病机制中不起主要作用。Hp感染不是肝硬化产生PHG的主要致病因素，对有Hp感染的PHG患者无需常规抗Hp根除治疗。