A facile and convenient approach for the one-pot synthesis of 2,4(1H,3H)-quinazolinediones

摘要

A fast and efficient method is described for the one-pot synthesis of 2,4(1H,3H)-quinazolinediones by cyclization reaction of anthranilic acid derivatives with potassium cyanate and acetic acid in PEG.Good to high yields of the products obtain in short reaction times with simple work-up.