蓝光联用中药治疗新生儿高胆红素血症的效果评价

摘要

目的 评价蓝光联用中药治疗新生儿高胆红素血症的效果.方法 60例新生儿高胆红素血症患者随机分为对照组和观察组,对照组采用常规蓝光治疗,观察组在此基础上,联用茵栀黄注射液治疗.结束后对两组患者的临床效果进行比较.结果 观察组和对照组治疗前血清总胆红素(TBiL)和未结合胆红素(IBil)差异不显著(P>0.05),但治疗后观察组TBiL为(125.40±24.50)μmol/L,明显低于对照组(158.20±29.60)μmol/L,具有显著差异(t=4.6755,P＜0.01);治疗后观察组IBiL为(91.10±11.50)μmol/L,明显低于对照组(97.90±12.30)μmol/L,具有显著差异(t=2.2119,P＜0.05).观察组在治疗后1～3 d黄疸消退,对照组在治疗后5～7 d黄疸消退.治疗期间两组均未见不良反应.结论 蓝光联用茵栀黄注射液治疗新生儿高胆红素血症效果好,而且安全,建议临床进一步推广.%Objective To evaluate the effects of Blu-ray combined with Chinese medicine treatment of the patients with Hyperbilirubinemia. Methods 60 cases with Hyperbilirubinemia in our hospital were randomly divided into observation group and control group each with 30 cases, and the control group was treated with Blu-ray, the observation group was treated with Blu-ray combined with Yinzhihuang Injection. The clinical results were compared for these two groups. Results Observation group and control group pre-treatment serum total bilirubin (TBiL) and unconjugated (IBil) no significant difference (P> 0.05), but after treatment TBiL for the observation group (125.40 ± 24.50) μmol / L, significantly lower than the control group (158.20 ± 29.60) μmol / L, with a significant difference (t = 4.6755, P＜0.01);IBiL after treatment for the observation group (91.10 ± 11.50) μmol / L, significantly lower than the control group (97.90 ± 12.30) μmol / L, with a significant difference (t = 2.2119, P＜0.05). Observer Group in the treatment of 1 ～ 3 d after the jaundice subsided, the control group after treatment at 5 ～ 7 d jaundice subsided. During treatment the two groups were no adverse reactions.Conclusions Blu-ray combined with Yinzhihuang Injection is effective in treatment of the patients with Hyperbilirubinemia,which should be suggested in clinical experiences.