冠心病介入治疗中冠脉内注射硝酸甘油与异舒吉的对比研究

摘要

With the wide application of PCI in clinical treatment and increased stable cases, National Health and Family Planning Commision requires that PCI must be applied under strict standard system. Nowadays, our hospital has improved treatment technique, medical equipment and operation quality. Therefore, the mortality rate of PCI is low. In China, coronary injection of nitrate during PCI is necessary, and that mainly includes nitroglycerin and isoket (isosorbide dinitrate). However, there is no clinical comparative research of these two coronary injection drugs. This paper provides observation of effectiveness and safety of nitroglycerin and isoket through coronary injection in PCI.%在临床治疗中，伴随PCI技术使用范围的不断推广，以及从该技术中病情获得稳定的病例数持续增加，我国卫计委要求介入手术一定要严格地执行标准体系。目前，本院介入治疗技术和医疗器械都得到提升，手术质量也得到提高，因此，介入治疗所引发的死亡率处于较低水平。在我国PCI操作过程中依据需要冠状动脉(冠脉)内注射硝酸酯，较多使用硝酸甘油，亦用异舒吉(二硝酸异山梨醇酯)，但临床上尚缺乏冠脉内注射两种药物头对头的比较研究。本文观察PCI术中冠脉内注射硝酸甘油与异舒吉的有效性和安全性。