炔雌醇环丙孕酮片治疗多囊卵巢综合征62例分析

摘要

OBJECTIVE: To investigate the therapeutic efficacy of polycystic ovary syndrome (PCOS) in the treatment of Ethinylestradiol and cyproterone acetate tablets. METHODS: 62 cases of PCOS were treated by Ethinylestradiol and cyproterone acetate tablets for 3 cycles. The serum levels of E2, FSH, LH, PRL and T, the size of ovary and the number of sinus follicle were determined before and after treatment CP<0.01 orP<0.05). RESULTS: The serum levels of FSH, LH, LH/FSH, T and PRL and the size of ovary and the number of sinus follicle decreased significantly after treatment for 3 cycles than before (all P<0.01). CONCLUSION: Ethinylestradiol and cyproterone acetate tablets can significantly improve hyperandrogenism in PCOS patient and be used for ovulation induction so as to promote the possibility of ovulation and pregnancy.%目的:观察口服炔雌醇环丙孕酮片治疗多囊卵巢综合征(PCOS)的疗效.方法:对62例已确诊的PCOS患者予炔雌醇环丙孕酮片治疗3个周期,测定患者治疗前、后雌二醇(E2)、促卵泡生成素(FSH)、黄体生成素(LH)、泌乳素(PRL)、睾酮(T)的水平并以B超测量卵巢大小及窦卵泡数的变化情况.结果:治疗3个周期后患者血清FSH、LH、LH/FSH、T、PRL均较治疗前明显下降(P＜0.01或P＜0.05),卵巢体积缩小,窦卵泡数减少(均P＜0.01).结论:炔雌醇环丙孕酮片能有效改善PCOS患者的高雄激素血症,并可用于PCOS患者促排卵治疗的前期用药,从而提高其排卵率和妊娠率.