OBJECTIVE:To establish the fingerprint of Artemisia apiacea to identify common model and evaluate the quality coherence of the commercially available A. apiacea decoration pieces in Chongqing. METHODS:HPLC method was performed on the column of Waters XTerra C18 with the mobile phase consisted of methanol-0.1% phosphoric acid(gradient elution)at the flow rate of 1.0 ml/min. The detection wavelength was 220 nm,column temperature was 30 ℃ and the sample size was 10 μl. The simi-larity of 12 batches of samples was evaluated by TCM Chromatogram Fingerprint Similarity Evaluation System(2004A edition);a common model of fingerprints was identified by principal component analysis(PCA)and cluster analysis(CA). RESULTS:Total-ly 11 batches of samples were screened to establish common model of fingerprints and 16 common peaks were obtained,among which,3 common components were identified;RSDs of precision,stability and reproducibility tests were lower than 2.53%. The similarity of 11 batches of A. apiacea and reference chromatogram was more than 0.990. CONCLUSIONS:The method is stable and easy,and can provide reference for the scientific quality evaluation and control of A. apiacea;the quality of commercially available A. apiacea decoration pieces is generally good,however,there is still a little number of batches with poor quality. The production procedures and supervision of A. apiacea decoration pieces should be strengthened.%目的：建立青蒿指纹图谱并对其共有模式进行识别，评价重庆市售青蒿饮片质量的一致性。方法：采用高效液相色谱法。色谱柱为Waters XTerra C18，流动相为甲醇-0.1％磷酸水溶液（梯度洗脱），柱温为30℃，流速为1.0 ml/min，检测波长为220 nm，进样量为10μl。利用《中药色谱指纹图谱相似度评价系统》（2004A版）对12批样品的相似度进行评价，并通过主成分分析、系统聚类分析对其进行共有模式识别。结果：筛选出11批样品，建立了指纹图谱共有模式，并标定了16个共有特征峰。经对照，指认出东莨菪内酯、青蒿素、青蒿酸3种主要成分；精密度、稳定性、重复性试验的RSD均≤2.53％。11批样品与对照图谱相似度＞0.990。结论：该方法稳定、易操作，可为科学评价和控制青蒿药材的质量提供参考依据。重庆市售青蒿饮片质量整体较好，尚有少量批次质量欠佳，应加强青蒿饮片规范化生产和监督。
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