江苏省药事管理质控中心在促进医院抗菌药物合理应用中的作用

摘要

目的:评价江苏省药事管理质控中心在促进医院抗菌药物合理应用中的作用.方法:介绍江苏省药事管理质控中心在促进抗菌药物合理应用方面的措施;通过收集由江苏省药事管理质控中心建立的"江苏省药事管理质控网报系统"中2014年1月-2017年1月的各项抗菌药物临床应用的相关数据(如抗菌药物处方比例、住院患者抗菌药物使用率等),分析质控中心在促进抗菌药物合理应用方面的作用.结果:质控中心制订及采取的各项措施包括严格落实抗菌药物分级管理和备案制度、开展抗菌药物临床应用基本情况调查等;共纳入65家医院的抗菌药物应用数据,分析结果表明,与2014年1月比较,2017年1月各样本医院门诊抗菌药物处方比例由18.37%降低至14.63%,急诊抗菌药物处方比例由34.94%上升至37.92%;住院患者抗菌药物使用率由56.11%降低至51.28%,抗菌药物使用强度由49.74降低至44.13;甲状腺、乳腺、疝气手术抗菌药物预防使用率由35.27%降低至8.88%,介入手术诊断抗菌药物预防使用率由12.55%降低至2.46%;住院患者抗菌药物病原学送检率从48.44%上升至54.60%.结论:江苏省药事管理质控中心通过3年多的质控管理,促进了省内65家医院的抗菌药物合理应用.%OBJECTIVE:To describe the effect of Jiangsu Pharmaceutical Management Quality Control Center(JPMQCC)on promoting the rational use of antibacterial agents in hospitals. METHODS:Measures in promoting the rational use of antibacterial agents taken by JPMQCC were introduced. Effect of quality control center on promoting the rational use of antibacterial agents was analyzed by collecting data(such as antibacterial prescription proportion,inpatients'use rate of antibacterial agents)about the clini-cal use of antibacterial agents during Jan. 2014-Jan. 2017 in"Jiangsu Pharmaceutical Management Quality Control Network Report-ing System"established by JPMQCC. RESULTS:Measures implemented and developed by quality center included strictly imple-menting classification management and filing system of antibacterial agents,and carrying out basic information survey for applying antibacterial agents,etc. Applying data of antibacterial agents in totally 65 hospitals were collected. Analysis results showed,com-pared with Jan. 2014,antibacterial prescription proportion for outpatient of sample hospitals in Jan. 2017 was decreased from 18.37% to 14.63%,and antibacterial prescription proportion for emergency was increased from 34.94% to 37.92%. Inpatients'use rate of antibacterial agents was decreased from 56.11%to 51.28%,and its intensity was decreased from 49.74 to 44.13. The preven-tive use rate for thyroid,breast and hernia surgery was decreased from 35.27% to 8.88%,and in interventional surgery diagnosis, it was decreased from 12.55% to 2.46%. Pathogenic detection rate of inpatients was increased from 48.44% to 54.60%. CONCLU-SIONS:The quality control management in JPMQCC for more than 3 years has promoted the rational use of antibacterial agents of 65 hospitals in Jiangsu province.