呼吸操、家庭氧疗联合沙美特罗氟替卡松干粉吸入剂治疗COPD稳定期患者的效果观察

摘要

目的：观察呼吸操、家庭氧疗联合沙美特罗氟替卡松干粉吸入剂治疗慢性阻塞性肺疾病(COPD)稳定期患者的效果。方法将符合标准的128例COPD稳定期患者随机分为观察组和对照组，各64例，两组均给予常规治疗，观察组加用呼吸操锻炼、家庭氧疗及沙美特罗替卡松干粉剂吸入剂治疗，随访1年，对比两组治疗前后的肺功能相关指标、临床疗效及急性加重情况等。结果观察组总有效率为92.19%，显著高于对照组的76.56%，两组比较差异有统计学意义(P<0.05)。两组治疗后的肺功能相关指标较治疗前均有改善，观察组改善更明显(P<0.05)。观察组急性加重次数>2次发生率低于对照组，差异有统计学意义(P<0.01)。两组急性加重发生频率比较差异无统计学意义(P>0.05)。结论呼吸操、家庭氧疗联合沙美特罗氟替卡松干粉吸入剂治疗COPD的效果确切，且能改善COPD患者的肺功能，减少急性加重次数。%Objective To observe the clinical efficacy of breathing exercise,home oxygen therapy combined with salme-terol fluticasone dry powder inhaler in the treatment of patients with stable chronic obstructive pulmonary disease (COPD). Methods 128 patients with stable COPD who met the standards were randomly divided into observation group and control group,with 64 patients in each group.Conventional treatment was used in two groups,breathing exercise, home oxygen therapy combined with salmeterol fluticasone dry powder inhaler were used in observation group.After 1-year followed-up,the related index of pulmonary function before and after the treatment,clinical efficacy and acute ex-acerbation situation in two groups was compared respectively. Results Total effective rate of observation group was 92.19%,significantly higher than that of control group (76.56%),with statistical difference between two groups (P<0.05). After the treatment,the related index of pulmonary function in two groups was improved than that before treatment re-spectively,the related index of pulmonary function in observation group was improved obviously than that in control group (P<0.05).The incidence rate of acute exacerbation more than 2 times in observation group was lower than that in control group,with statistical difference (P<0.01).Occurrence frequency of acute exacerbation in two groups was cpm-pared,with no statistical difference(P>0.05). Conclusion Breathing exercise,home oxygen therapy combined with salme-terol fluticasone dry powder inhaler shows accurate efficacy in the treatment of patients with COPD and can improve the patients’pulmonary function and reduce acute exacerbation times.