卡前列素氨丁三醇在剖宫产同时行子宫肌瘤剔除术中的临床应用

摘要

目的：探讨卡前列素氨丁三醇在剖宫产同时行子宫肌瘤剔除术中的应用价值。方法抽取2014年1月~2015年1月本院收治的60例剖宫产同时行子宫肌瘤剔除术患者作为研究对象，将其随机分为两组，对照组给予缩宫素治疗，观察组给予卡前列素氨丁三醇治疗，记录两组患者手术时间、术中出血量、糖化血红蛋白、产后恶露时间及术中用药不良反应发生率。结果观察组患者的手术时间、术中出血量、糖化血红蛋白值下降幅度、产后恶露天数分别为(41.62±8.67)min、(218.67±94.67)ml、(1.28±0.66)g/L、(23.84±3.61)d，均优于对照组，差异有统计学意义(P<0.05)。两组患者用药不良反应的发生率比较，差异无统计学意义(P>0.05)。结论剖宫产同时行子宫肌瘤剔除术中采用卡前列素氨丁三醇进行预防止血，能减少术中出血量，提高手术治疗安全性。%Objective To explore the application value of carboprost tromethamine in cesarean section and myomecto-my simultaneously. Methods 60 patients undergone cesarean section and myomectomy simultaneously in our hospital from January 2014 to January 2015 were selected as research objects.They were randomly divided into two groups.In control group,oxytocin was applied,while in observation group,carboprost tromethamine was provided.The operation time, intraoperative amount of bleeding,glycosylated hemoglobin,time of postpartum lochia and intraoperative incidence of adverse drug reaction between two groups was recorded respectively. Results In observation group,operation time,intra-operative amount of bleeding,decreased value of glycosylated hemoglobin,time of postpartum lochia were (41.62±8.67) min,(218.67±94.67) ml,(1.28±0.66) g/L,and (23.84±3.61) d,much better than that of control group respectively,with sta-tistical difference(P<0.05).There was no significant difference in incidence of adverse drug reaction between two groups (P>0.05). Conclusion Carboprost tromethamine used for bleeding prevention during cesarean section and myomectomy simultaneously can reduce intraoperative blood loss and improve the safety of surgery.