Objective To compare the clinical effect of three different root canal filling materials in oral medicine in the treatment of one-time root canal therapy. Methods Collecting 213 patients,330 teeth in writer's outpatient from January 2010 to January 2011, randomly divided into three groups, treated with different root canal filling materials: Vitapex sealer (group A), Cortisomol sealer(group B) and zinc oxide clove oil iodoform paste (group C), to compare after one week treatment in patients with pain and the cure rate after one year later. Results The root canal therapy after one week, A group of pain was 13.6%, and 16.4% for group B, C group is 28.2%,group C was significantly higher than A and B group (P <0.05); Group C pain score significantly higher than A, B group (P <0.05); one year later, the cure rate of A group was 91.2% and 90.0% of group B, C group was 79.1%, the group C was significantly lower than the A and B group (P <0.05); A and B group compared, the difference was not statistically significant (P >0.05). Conclusion In the same operating conditions, Vitapex sealer and Cortisomol sealer than iodoform paste zinc oxide clove oil sealer have better effects,they are ideal root canal filling materials.% 目的对比口腔内科3种不同的根管填充材料在一次性根管治疗中的临床效果.方法2010年1月~2011年1月于笔者所在门诊收治的各类牙髓炎、根尖周炎需进行根管治疗的患者共213例,330颗牙.随机分为3组,分别采用Vitapex 糊剂(A 组)、Cortisomol 糊剂(B 组)以及碘仿氧化锌丁香油糊剂(C 组)进行根管填充,比较3组根管填充治疗1周后患者疼痛情况及术后1年的治愈率.结果根管治疗1周后,A 组疼痛发生率为13.6%,B 组为16.4%,C 组为28.2%, C 组疼痛发生率明显高于 A、B 组(P <0.05)；C 组疼痛评分明显高于 A、B 组(P <0.05)；1年后 A 组治愈率为91.2%,B组为90.0%,C 组为79.1%,C 组明显低于 A、B 组(P <0.05)；A、B 组比较,差异无统计学意义(P >0.05).结论在同等的操作条件下 Vitapex 糊剂、Cortisomol 糊剂比碘仿氧化锌丁香油糊剂有更好的疗效,是较为理想的根充材料.
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