2010～2012年我院深部抗真菌药使用情况分析

摘要

Objective To evaluate the utilization of deep antifungal drugs in our hospital,so as to provide evidence for the effective management of medication. Methods The defined daily dose (DDD) was used as the unit.The usage figure and consumption sum of deep antifungal drugs,DDC,DUI and AUD were analyzed in our hospital from 2010 to 2012. Results The kinds, usage figure and consumption sum of deep antifungal drugs were increasing over the 3 years.The consumption sum of Fluconazole was accounted for more than 70% of all deep antifungal drugs in three years.And the antibiotics use densities (AUD) of deep antifungal drugs presented clearly growing trend. Conclusion In order to promote the rational use of deep antifungal drugs,the causes should be further analyzed.%目的：对我院深部抗真菌药物的使用情况进行统计与评价，为临床合理用药和有效管理提供参考。方法使用限定日剂量（DDD）作为分析单位，计算累积DDDs，并以此为基础对2010～2012年我院（二级甲等）住院患者的深部抗真菌药物用药数量与金额、日均费用（DDC）、药物利用指数（DUI）、药物使用强度（AUD）进行统计计算。结果我院深部抗真菌药品种、使用数量和销售金额均呈逐年上升趋势。氟康唑是治疗深部真菌感染的主要药品。深部抗真菌药的用药强度逐年增长趋势明显。结论为促进抗菌药物合理应用，需进一步分析原因，加强监控。