首页> 中文期刊> 《中国医药科学》 >高压氧对脑肿瘤、脑动脉瘤术后康复疗效的观察

高压氧对脑肿瘤、脑动脉瘤术后康复疗效的观察

         

摘要

Objective To investigate the clinical effect of hyperbaric oxygen (HBO) in the treatment of brain tumors and cerebral aneurysms. Methods 200 patients with brain tumors or cerebral aneurysms in our hospital from 2009 December to 2013 December were selected, they were divided into two groups according to the different treatments. 100 cases with brain tumors or cerebral aneurysms were as the observation group that treated by HBO. 100 cases with similar disease were as the control group that treated without HBO. The two groups were both given conventional drug treatment .Checked cerebral vasospasm (CVS) by head color Doppler ultrasound, evaluated clinical recovery by neurological function and activities of daily living assessment, the clinical efficacy were compared and analyzed. Results The NF score and Barthel score of the two groups had no significant difference before the treatment (P>0.05);the NF score and Barthel score of the two groups had significant difference after the treatment (P < 0.05), Middle cerebral artery flow velocity and CVS of the two groups had no significant difference before the treatment(P>0.05), Middle cerebral artery flow velocity and CVS of the two groups had significant difference after the treatment(P<0.05). Conclusion HBO comprehensive treatment effect is remarkable, it can reduce neurological deficits, improve the quality of patients' life, it should be introduced.%目的:探讨高压氧(HBO)治疗脑肿瘤、脑动脉瘤术后康复的临床疗效。方法选取我院2009年12月~2013年12月收治的脑肿瘤、脑动脉瘤术后患者200例,根据治疗方法不同分为两组,将100例HBO治疗的脑肿瘤、脑动脉瘤术后患者设为观察组,将病情相似未作HBO治疗的100例患者设为对照组,两组均常规药物治疗。采用头颅彩色多普勒超声检查患者脑血管痉挛(CVS)情况,并采用神经功能缺损评分和日常生活活动能力评定评判患者临床恢复情况,并对临床疗效进行对比分析。结果两组患者治疗前NF评分和Barthel评分比较差异无统计学意义(P>0.05);观察组患者治疗后NFD评分和Barthel评分与对照组治疗后比较差异均有统计学意义(P<0.05);两组患者治疗前大脑中动脉流速及CVS比较差异无统计学意义(P>0.05);观察组患者治疗后大脑中动脉流速及CVS与对照组治疗后比较差异均有统计学意义(P<0.05)。结论HBO综合治疗效果显著,能够减少神经功能缺损评分,提高患者生活质量,值得推广使用。

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