临床药师在抗菌药物合理使用中的作用及效果分析

摘要

Objective To explore the role and efficacy of clinical pharmacists in the comprehensive intervention management of rational use of antibacterial drugs.Methods Clinical pharmacists participated in the whole process of intervention management of antibacterial drugs.400 cases before intervention and 400 cases after intervention were randomly abstracted from the hospitalized records for retrospective study,the use of antibacterial drugs was compared and analyzed.ResultsAfter intervention,the usage rate,the expense and the preventive usage rate of antibacterials,mean hospital stay and irrational use of antibiotics dropped obviously(P<0.01 orP<0.05). Conclusion Rational use of antibacterial drugs in clinic and the delay of generation of tolerant bacterial strains can be achieved by participation of clinical pharmacists in the comprehensive intervention management.%目的 探讨临床药师在抗菌药物合理使用中的综合干预作用及效果.方法 临床药师积极参与医院抗菌药物管理的全过程,从干预前后的住院病历中各随机抽取400份进行回顾性调查,对比分析干预前后抗菌药物的使用情况.结果 干预后抗菌药物使用率、抗菌药物费用、预防性用药比率、平均住院天数及各种抗菌药物不合理使用发生率均有明显下降(P<0.01或P<0.05).结论 通过临床药师的积极参与可有效提高抗菌药物使用的合理性,延缓耐药菌的产生.