自拟中药方联合西药治疗中重度慢阻肺急性发作期的效果分析

摘要

目的：探讨自拟中药方联合西药治疗中重度慢阻肺（AECOPD）急性发作期的疗效分析及安全性。方法将2013年1月~2015年9月入住我院的68例AECOPD患者按照治疗方法分为对照组（32例）与治疗组（36例）。两组患者均首先接受常规治疗，对照组在常规治疗基础上给予自拟中药汤剂口服，治疗后比较两组治疗效果及安全性。结果治疗后，治疗组临床总有效率为91.7%（33/36），对照组为68.8%（22/32），差异具有统计学意义（P＜0.05）；两组患者治疗后临床症状评分、呼吸困难分级、PaCO2、FEV1及PaO2水平均较治疗前明显改善（P＜0.05），且治疗组患者治疗后各指标均优于对照组（P＜0.05）；且未见明显毒副反应。结论中西医结合治疗中重度AECOPD具有肯定疗效，安全性高。%Objective To explore the Clinical efficacy and safety of traditional Chinese medicine Combined with Western medicine in the Treatment of acute Attack of Moderately Severe COPD.Methods68 cases with AECOPD were allocated to control group (32 cases) and treatment group(36 cases) follow to the treatment methods. All the patients were received conventional therapy and patients in the treatment group were also treated with traditional Chinese medicine. After treatment, the curative effect of two groups and safety were compared between the two group and before treatment.Results After treatment, the clinical efficacy were 91.7%(33/36) and 68.8%(22/32) for the treatment and control group respectively with statistical difference(P<0.05). The symptom score, dyspnea grading, PaCO2,FEV1 and PaO2 were significant better after treatment in both groups(P<0.05).And all the above index were significant different between the two groups after treatment(P<0.05).No significant drug related toxicity were found. Conclusion Traditional Chinese medicine Combined with Western medicine has a positive curative effect in the treatment of moderately severe COPD,and it’s safe.