光学相干断层扫描在老年性黄斑变性诊断中的应用价值研究

摘要

Objective To explore the application value of optical coherence tomography (OCT) in the diagnosis of age-related macular degeneration (AMD).Methods 72 AMD patients who were treated in our hospital from October 2013 to March 2015 (104 eyes) were selected. All patients (104 eyes) received OCT, retinal thickness analysis (RTA), and Heidelberg retina tomography (HRT). The detection efficiency of three methods were analyzed and compared. Results The detection rate of OCT was significantly higher than that of RTA and HRT in the detection of drusen, geographic atrophy, and choroidal neovascularization (CNV). The difference was statistically significant (P<0.05). Compared with RTA and HRT, OCT showed no obvious difference in the detection rate of pigment epithelium detachment (PED). There was no significant difference (P>0.05). ConclusionCompared with RTA and HRT, OCT has a higher positive detection rate of AMD, higher specificity and sensitivity, and less harm to the body. It is worthy to be popularized in clinical diagnosis.%目的：探讨光学相干断层扫描（OCT）在老年性黄斑变性（AMD）诊断中的应用价值。方法选取2013年10月～2015年3月至我院就诊的72例（104只眼）老年性黄斑变性患者作为研究对象，对所有患者（104只眼）行光学相干断层扫描（OCT）、视网膜厚度分析（RTA）和共焦激光断层扫描（HRT）检测，分析比较三种检测方法的检测效率。结果OCT检测对患者的玻璃膜疣、地图状萎缩、脉络膜新生血管（CNV）等症状检出率明显高于RTA和HRT，差异比较有统计学意义（P＜0.05）；与RTA 和HRT相比，OCT检测对患者的眼视网膜色素上皮脱落(PED)检出率无明显差异，差异比较无统计学意义（P＞0.05）。结论与RTA检测和HRT检测相比，OCT对老年性黄斑变性的阳性检出率更高，具有较高的特异性及灵敏性，对机体伤害小，值得在临床诊断中推广应用。