首发精神分裂症未治疗时间与早期症状临床分析

摘要

Objective: To investigate the clinical analysis on duration of untreated psychosis (DUP) and early symptoms of first-episode schizophrenia. Methods: Psychotic symptoms rating scale (SOS) was used to evaluate the early symptoms and DUP of 100 patients eligible for the first-episode schizophrenia in CCMD-Ⅲ.Results: Early symptoms with the incidence rate of over 40％ and lasting more than 6 months were sleep disturbance, role dysfunction, suspicion, bizarre behaviors, emotional disorders, ideas of reference, abnormal perception, paranoia, abulomania and so on. The median DUP was 26 months and the long DUP was relevant to negative symptoms. Conclusion: The early identification of early symptoms, strengthening publicity of mental health knowledge and shortening DUP are very important.%目的:探讨首发精神分裂症未治疗时间(DUP)及患者早期症状临床分析.方法:对100例符合<中国精神障碍分类与诊断标准(第3版)>(CCMD-Ⅲ)中精神分裂症首次发作的患者应用首发精神分裂症精神症状评定量表(SOS)评定早期症状及患者的DUP.结果:发生率＞40%、持续时间超过6个月的早期症状依次有睡眠障碍、角色功能障碍、疑心、怪异行为、情绪障碍、牵连观念、知觉异常、妄想、意志缺乏等.DUP中位数为26个月且长DUP与阴性症状相关.结论:尽早识别早期症状,加强精神卫生的知识宣传,缩短DUP非常重要.