糖皮质激素对大鼠各组织ENaC的影响

摘要

Epithelial sodium channel is composed of three subunits, α, β and γ.It's responsible for the rate-limiting reabsorption of sodium ions.It plays an important role in the self-maintaining sodium balance, extracellular fluid volume and blood pressure.Glucocorticoids can affect the activity of sodium channels, thereby affect the production and cure of many diseases.%上皮钠离子通道由α、β、γ三个亚单位组成,负责钠离子的限速重吸收,对于维持钠的自身平衡、细胞外液量和血压起重要作用.糖皮质激素可以通过影响钠离子通道的活性,进而影响许多疾病的产生和痊愈.