Objective To observe the clinical therapeutic effect and safety of Reduning Injection plus antimicrobial drug in the treatment of community acquired pneumonia. Methods 124 patients with community acquired pneumonia were randomly divided into two groups, the treatment group and the control group, each had 62 cases. The patients in control group were treated with antimicrobial conventional drugs; the patients in treatment group were treated with Reduning Injection for 7?10 days on the basis of conventional drugs. Clinical symptom and the body temperature were observed. Results The total effective rate in the treatment group (96.77%) was significantly higher than that in control group (90.32%) (P < 0.05). The clinical symptom in both groups had significant improvement as compared with before treatment, with the time of control febrile and cough in treatment group was shorter than in control group, there were significant differences between the two groups (P < 0,05). There was a significant difference of CRP of the two groups after treatment (P < 0.05). There was no severe untoward reaction occurred in the two groups. Conclusion Reduning Injection plus antimicrobial drug is a safe and good method in the treatment of community acquired pneumonia. It can be used to treat community acquired pneumonia as an effective drug.%目的 分析研究热毒宁联合抗生素治疗社区获得性肺炎的临床疗效及安全性.方法 将124例肺炎住院患者随机分为治疗组和对照组各62例,对照组患者按社区获得性肺炎指南给予抗菌药物治疗,治疗组在按社区获得性肺炎指南给予抗菌药治疗的基础上加用热毒宁注射液20 mL,1次/d,疗程7～10 d.观察两组治疗前后的临床症状、体温变化.结果 治疗组有效率为96.77%,对照组为90.32%,两组比较差异有统计学意义(P < 0.05);治疗组在控制发热、咳嗽症状恢复天数方面明显短于对照组(P < 0.05);两组治疗后C反应蛋白(CRP)比较差异有统计学意义(P < 0.05);两组均未见明显的毒副作用与不良反应.结论 热毒宁注射液联合抗生素治疗社区获得性肺炎安全性高,疗效较好,可作为社区获得性肺炎的有效治疗方法之一.
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