炎症性肠病患者焦虑、抑郁状态分析及其与生活质量的关系

摘要

目的 分析炎症性肠病患者焦虑、抑郁状态,探讨其与生活质量的关系.方法 选择2015年9月～2017年1月河北省人民医院门诊及住院确诊的炎症性肠病患者60例(IBD组)及同期健康体检者60例(正常组),使用焦虑自评量表(SAS)、抑郁自评量表(SDS)进行焦虑、抑郁状态评价,使用炎症性肠病生存质量问卷(IBDQ)进行生活质量评价.结果 IBD患者焦虑、抑郁发生率分别为45.0％、60.0％,明显高于正常组的3.3％、6.7％(P＜ 0.05);IBD患者的焦虑、抑郁评分明显高于正常组,组间比较差异有统计学意义(P＜0.05);焦虑、抑郁程度不同,IBD患者的IBDQ评分间差异有统计学意义(P＜0.05);IBD患者的SAS、SDS评分均与IBDQ评分呈明显负相关(P＜0.05).结论 炎症性肠病患者的焦虑、抑郁发生率明显高于正常人群,并且焦虑、抑郁程度越严重,生活质量越低,进行针对性治疗有助于改善预后.%Objective To analyze the anxiety and depression of patients with inflammatory bowel disease,and explore their relationship with the quality of life.Methods 60 patients with inflammatory bowel disease treated in Hebei People's Hospital from September 2015 to January 2017 were selected as IBD group,and 60 cases with physical examina tion in the same period were selected as normal group.Self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were used to evaluate the anxiety and depression status of patients,and the quality of life was evaluated using the inflammatory bowel disease quality of life questionnaire (IBDQ).Results The incidence rates of anxiety and depression in IBD group were 45.0％ and 60.0％,which were significantly higher than 3.3％ and 6.7％ in normal group (P ＜ 0.05).The anxiety and depression scores in IBD group were significantly higher than those in normal group (P ＜ 0.05).In IBD group,with different levels of anxiety and depression,the IBDQ scores of patients were also statistically significant (P ＜0.05).There were significant negative correlations between SAS,SDS scores and IBDQ score in IBD patients (P ＜0.05).Conclusion The incidence rates of anxiety and depression in patients with inflammatory bowel disease are significantly higher than the normal population,and the quality of life decreased with the serious anxiety and depression,with the targeted treatment can help to improve the prognosis of patients.