高血压是全球性的主要公共卫生问题之一，我国同样面临着严峻的高血压问题，估计我国目前约有2亿高血压患者，约占全球高血压总数的20%。而顽固性高血压治疗又是高血压治疗中的重点及难点。近年来，以SymplicityTM为代表的利用射频能量行去肾交感神经术的出现给顽固性高血压治疗带来了新的希望。但其仍存在诸如只能进行单点消融，消融效率较低，手术时间和射线接触时间长等缺陷。而随着新的消融系统的不断研发成功，出现了许多更加安全有效的导管消融系统。本综述从射频消融导管系统、射频消融球囊系统及化学消融三方面对去肾交感神经术的相关新型导管器械研发进展作一阐述。%Nowadays, hypertension as one of the major global public health burdens, affects 200 million Chinese and 1 billion people worldwide. To date, the treatment of resistant hypertension remains a great challenge in the management of hypertension. In recent years, represented by the SymplicityTM System, Catheter-based renal denervation (RDN), specifically targeting renal sympathetic nerves, has become a novel technique for the treatment of resistant hypertension with great promises. Nonetheless, defects of this novel technique are also obvious, e.g. low efficiency, prolongation of operative time and radiation exposure time due to the only strategic option of point by point ablation, etc. While on the other hand, with the rapid developments of new ablation systems, more and more catheter ablation systems with greater safety and efficacy have become available. This review will focus on the developments of radiofrequency ablation catheter system, radiofrequency ablation balloon system and chemical ablation, which are all closely related to RDN.
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