原发性皮肤CD30＋间变性大细胞淋巴瘤一例

摘要

A 50-year-old male presented with multiple nodules on the back and chest with mild tenderness over half a year. Biopsy showed epidermal hyperkeratosis, stratum spinosum hypertrophy, anaplastic diffuse large lymphocytes in dermal layer and subcutaneous tissue and mitotic figure presented. Immunohistochemis-try showed 85% cells of CD30 (++) , 40% of Ki- 67 (+) , CD3 (++) , LCA (+) . The diagnosis of prima-ry cutaneous CD30+ anaplastic large cell lymphoma, T cell type was made.%患者,男,50岁。背部、前胸多发结节伴轻压痛半年余。皮损组织病理检查示：表皮角化过度、棘层肥厚；真皮全层及皮下组织间变性弥漫肿瘤细胞浸润、瘤细胞体积大,可见核分裂相。免疫组化结果：85％ CD30强阳性,Ki－67约40％(＋),CD3(＋＋),LCA(＋)。诊断：原发性皮肤CD30＋间变性大细胞淋巴瘤,T细胞型。