红宝石点阵激光联合强脉冲光治疗黄褐斑102例疗效评价

摘要

目的:评价红宝石点阵激光联合强脉冲激光治疗黄褐斑临床疗效及安全性.方法:102例黄褐斑患者给予Q开关红宝石点阵激光治疗,能量密度2.5～ 3.5 J/cm2,2周后,行强脉冲光治疗.每4周治疗1次,共4次.治疗结束前后对患者进行黄褐斑皮损面积和严重程度指数(MASI)评分,记录复发情况及不良反应.治疗结束后6个月随访判定结果.结果:痊愈5例(4.90％),显效69例(67.65％),好转26例(25.49％),无效2例(1.96％),总有效率72.55％.未见明显不良反应.结论:红宝石点阵激光联合强脉冲光治疗黄褐斑安全、有效.%Objective:To assess the efficacy and safety of ruby dot matrix laser combined with intense pulsed light in the treatment of melasma.Methods:One hundred and two patients with melasma were firstly treated with ruby dot matrix laser (energy density of 2.5～3.5 J/cm2) and followed by intense pulsed light after 2 weeks.The treatment was repeated every 4 weeks for 4 times.The severity and the area of melasma were assessed by melisma area severity index (MASI).The recurrence and adverse reaction were also assessed.The therapeutic efficacy was assessed in 6 months after the end of the treatment.Results:Five patients (4.90％)were cured,69 patients (67.65％) improved remarkably,26 patients (25.49％) improved and 2 patients were not effective.There were no side effects in all the patients.Conclusion:Ruby dot matrix laser combined with intense pulsed light is safe and effective in the treatment of melasma.