左炔诺孕酮宫内缓释系统治疗腹腔镜术后复发性卵巢子宫内膜异位症患者的临床研究

摘要

[Objective] To investigate the effect of recurrent endometriosis after laparoscopy treated by levonorgestrel-releasing intrauterine device (LNG-IUD).[Methods] 90 patients with recurrent endometriosis after laparoscopy were treated with LNG-IUD.The effect and side effects were compared 3,6,12 months after treatment.[Results] In 3,6,12 months after treatment,the score of dysmenorrheal,pelvic cavity tenderness and sexual intercourse pain decreased gradually,the volume of ovarian cyst lessened gradually,the level of CA125 decreased gradually (P ＜0.05).[Conclusions] LNG-IUD may effectively kill the pain of recurrent endometriosis,lessen the volume of ovarian cyst and less side effect.It's an effective,safe and high compliance method.%目的 探讨左炔诺孕酮官内缓释系统(LNG-IUS)应用于腹腔镜下卵巢子宫内膜异位症保守性手术后复发患者的临床疗效.方法 对90例行腹腔镜下卵巢子宫内膜异位症保守性手术后复发患者,术后放置LNG-IUS,随访其疗效和副反应.结果 放置前和放置LNG-IUS后3、6和12个月,痛经、慢性盆腔痛或性交痛的疼痛评分逐渐下降,卵巢囊肿体积逐渐变小,血清CA125水平逐渐下降,各时间段比较,差异均有显著性(P＜0.05).结论 LNG-IUS可以有效缓解腹腔镜下内异症保守性手术治疗后复发性患者的疼痛症状,降低血清CA125水平,缩小卵巢内异症囊肿体积,副作用少,对复发性患者是一种有效、安全及依从性高的治疗方法.