Obejective To evaluate the outcome at a 2 and 5 year follow-up whether combined arthroscopic surgery followed by exercise therapy was superior to the same exercise therapy alone when treating non-traumatic, degenerative medial meniscal tears. Methods Prospective cohort study was used in this study, 96 middle-aged patients with MRI verified degenerative medial meniscus tear and radiographic osteoarthritis grade ≤ 1 participated in the study. Radiographic examination was done before randomization and after 5 years. The patients were randomly assigned to either arthroscopic treatment followed by exercise therapy for 2 months or to the same exercise therapy alone. At the start of the study and at the follow-ups at 24 and 60 months the patients answered three questionnaires KOOS, Lysholm Knee Scoring Scale and Tegner Activity Scale and made pain ratings on the Visual Analogue Scale (VAS). Results Both groups showed highly significant clinical improvements from baseline to the follow-ups at 24 and 60 months on all subscales of KOOS, Lysholm Knee Scoring Scale and VAS (P = 0.000). No group differences were found at any of the testing occasions. One third of the patients that were treated with exercise therapy alone did not feel better after the treatment but were improved after arthroscopic surgery. According to radiographic findings two patients from each group had a slight progression of their osteoarthritis after 5 years. Conclusion The findings indicate that arthroscopic surgery followed by exercise therapy was not superior to the same exercise therapy alone for this type of patients. Consequently, exercise therapy can be recommended as initial treatment. However, one third of the patients from the exercise group still had disabling knee symptoms after exercise therapy but improved to the same level as the rest of the patients after arthroscopic surgery with partial meniscectomy.%目的 通过治疗后2和5年跟踪随访评价关节镜治疗联合运动疗法治疗非外伤性退行性膝关节内侧半月板损伤的疗效.方法 该研究为前瞻性队列研究,纳入96例磁共振成像(MRI)证实的退行性内侧半月板损伤及Kellgren-Lawrance(K-L)放射线分级≤1级的中年患者.患者随机分组前和治疗后5年接受影像学评估.患者随机分为两组,一组接受关节镜手术,随后行运动疗法2个月;另一组只行运动疗法.实验开始时,以及随访24和60个月时,患者接受3份调查问卷:膝关节损伤和骨关节炎结果评分(KOOS)、Lysholm膝关节评分量表和Tegner活动水平评定量表,并采用视觉模拟评分法(VAS)评估患者疼痛情况.结果 两组患者随访24和60个月时KOOS所有分量表、Lysholm膝关节评分和VAS评分与基线时相比,均获得显著改善,差异有统计学意义(P=0.000),而两组间同一时间点随访结果均无差异.但是1/3的只接受运动疗法患者感到效果不明显,又接受了关节镜手术.随访5年时影像学结果显示每组均有2名患者骨关节炎轻度进展.结论 关节镜手术联合运动疗法治疗非外伤性退行性内侧半月板损伤患者的疗效并不优于只行运动疗法.因此,运动疗法可作为初始治疗方案.然而,1/3的只行运动疗法组患者膝关节症状未得到缓解,随后行关节镜下半月板部分切除术后恢复.
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