Objective To study clinical ef ect of Erythromycin combined with Azithromycin in treatment of mycoplasma pneumonia in children. Methods 43 children patients with mycoplasma pneumonia were chose in our hospital from February 2014 to January 2015 and the patients were divided into two groups according to random number table. There were 23 patients in study group who were given Erythromycin combined with Azithromycin medication treatment. There were 20 patients in control group who were given Azithromycin medication treatment only. Treatment ef ects were compared between two groups after treatment. Results The recovery rate and improvement rate of study group were 78.3%and 95.7%which were much higher than that were 50.0%and 85.0%in control group. The rate of adverse ef ects was 8.7%in study group which was much lower than that was 20%in control group(P<0.05). Conclusion The ef ect of erythromycin combined with azithromycin medication is prominent in treatment of children patients with mycoplasma pneumonia. It is conducive to increasing recovery rate and improvement rate of children patients and reducing rate of adverse ef ects.%目的：分析红霉素联合阿奇霉素治疗小儿支原体肺炎的临床效果。方法搜集本院儿科诊治的2014年2月～2015年1月期间的43例小儿支原体肺炎患儿，按照随机数表法分为两组，研究组23例采用红霉素联合阿奇霉素，对照组20例采用单纯阿奇霉素，对比治疗效果。结果两组比较，研究组患儿痊愈率78.3%、治疗总好转率为95.7%，高于对照组的50.0%、85.0%；不良反应比较，研究组的发生率8.7%，低于对照组的20.0%（P<0.05）。结论红霉素与阿奇霉素联合治疗小儿支原体肺炎的效果显著，患儿的痊愈率高、治疗总好转率高，且不良反应的发生率低。
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