Objective To analyze and explore the risk factors of nosocomial infection in elderly patients. Methods From June 2013 to June 2015, 1060 cases of elderly patients in Department of orthopedics in our hospital as the research object, the clinical data were retrospectively analyzed. Results 1060 cases of elderly patients in Department of orthopedics, includ-ing 105 cases of infection, infection rate of 9.91%, 40 cases of male, 57 cases of female, aged (62~93), the average (77.2± 3.7) years of age, admission time and operation are independent risk factors of nosocomial infection in elderly patients. Conclusion Elderly patients with basic diseases in Department of orthopedics, because of the operation, long time and age have a very important relationship, these are important factors leading to the increase of infection rate in elderly patients, medical personnel should be actively treated at the same time to find prevention and attention, the patients with basic dis-eases must be active treatment of the original disease, elderly patients with nutritional and albumin, improve the patient's health care, and to increase the confidence of patients with disease.%目的：进一步分析和探讨高龄骨科住院患者医院感染危险因素分析。方法选取2013年6月—2015年3月该院骨科高龄患者1060例作为研究对象，对其临床相关资料进行回顾性分析。结果该院骨科高龄患者1060例，其中感染97例，感染次数105次，医院感染率9.91%，其中男性40例，女性57例，年龄在62~93岁，平均(77.2±3.7)岁，老年骨科患者医院感染的相关危险因素包括：性别、年龄、入院时间和手术是高龄骨科患者院内感染的独立危险因素，即P<0.05；导尿管留置与总感染率没有直接相关性。结论高龄骨科患者在伴有基础疾病外，由于手术、长时间卧床以及年龄都有着非常重要的关系，这些都是导致高龄患者感染率增加的重要因素；医务人员应在积极治疗的同时找到预防的关键并引起重视，对有基础疾病的患者一定要积极治疗原发病，老年患者多补充营养和白蛋白，提高老年患者的自身免疫力，机密关注患者的各项指标并给与相应的措施，增加患者战胜疾病的信心，稳定病人情绪这些对降低高龄患者医院感染都具有重要意义。
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