宫颈癌前期调强放疗与常规体外照射疗效比较

摘要

目的：比较宫颈癌前期调强放疗与常规体外照射疗效。方法选择2009年9月-2010年9月在临沂市肿瘤医院初治宫颈癌患者80例的临床资料进行回顾性分析。结果前期调强组总生存率(66.8%)明显高于常规放疗组(30.4%)(P=0049)》常规放疗局部肿瘤消退时间(6.86±1.74)明显低于前期调强组(4.19±1.54)(P<0.01)》前期调强组急性膀胱直肠反映发生率明显低于常规组(P<0.05)》阴道狭窄骨髓抑制﹑晚期放疗反应均差异无统计学意义(P>0.05)。结论前期调强放疗可提高初治宫颈癌患者近期生存率及局部肿瘤控制率，并能减轻患者的部分急性放射性损伤。%Objective To compare the effects between IMRT and conventional external radiation therapy on early cervical cancer. Methods The clinical data of 80 cases with cervical cancer initially treated in Linyi Tumor Hospital from September 2009 to September 2010 were selected and analyzed retrospectively. Results The overall survival rate (66.8%) of the group intervened by IMRT in early stage (IMRT group) was significantly higher than that(30.4%) of the conventional radiotherapy group (P=0049); the local tumor regression time of the conventional radiotherapy group (6.86 ± 1.74) was obviously shorter than that of the IMRT group (4.19 ± 1.54) (P<001); the incidence of acute bladder rectum reaction of the IMRT group was obviously lower than that of the nor-mal group (P<0.05); bone marrow suppression of vaginal stenosis, late radiation reactions were not statistically significant (P>0.05). Conclusion Intensity modulated radiation therapy in early stage can improve the short-term survival rate and local tumor control rate of the patients with cervical cancer treated initially, and alleviate part of the acute radiation injury of the patients.