Objective to analyze the clinical characteristics of open craniocerebral trauma complicated with intracranial foreign bodies,summarize the clinical treatment experience.Method take the medical records from the 23 cases of open craniocerebral injury combined with intracranial foreign bodies,carry out retrospective analysis;a first-aid: initial debridement,associated injury and high fatal trauma control;two stage depth debridement; three stage using stereotactic technology,navigation technology deep foreign body extraction.Results a period of emergency were scheduled for surgical treatment, 8h debridement of 16 people,1 people died;22 cases of two stage debridement,21 cases of large residual successful extraction of deep foreign body,1 cases of intracranial foreign body is small and multiple,not removed,2 patients died; 19 patients survived,good recovery of patients in 8 cases, in patients with disability in 8 cases,severe disability in patients with 2 cases,plant survival in patients with 1 cases; a first-aid implement time less than 8h in 1 cases of patients with poor prognosis,>8h patients with 6 cases,with significant difference(P<0.05);there were 3 deaths.Conclusion timely emergency,staging treatment is the key to save open craniocerebral trauma complicated with intracranial foreign bodies in the life; identification and discovery,timely treatment of intracranial hematoma,infection and other complications is very necessary.%目的：分析开放性颅脑外伤合并颅内异物临床特征,总结临床处理经验。方法调取23例开放性颅脑损伤合并颅内异物患者病历资料,进行回顾性分析；一期急救：初步清创、控制合并伤与高致死性创伤；二期深度清创；三期利用立体定向技术、导航技术摘除深处异物。结果一期急救均安排手术治疗,8 h内清创16例,死亡1例；22例行二期清创,21例大块残留者成功摘除深部异物,1例颅内异物细小、多发未摘除,死亡2例；19例患者存活,恢复良好8例,中残疾8例,重度残疾2例,植物生存1例；一期急救落实时间≤8 h者预后不佳1例、＞8 h者预后不佳6例,差异有统计学意义(P<0.05)；共死亡3例。结论及时急救、分期处理是挽救开放性颅脑外伤合并颅内异物患者生命的关键；鉴别与发现、及时处置颅内血肿、感染等并发症非常必要。
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