Objective To study the relevant treatment method and application effect of preterm premature rupture of mem-brane complicated by premature delivery. (Pregnant week was between 28 weeks to 34 weeks). Methods The clinical data of 108 cases of patients with preterm premature rupture of membrane complicated by premature delivery admitted and treated in out-patient department of our hospital were retrospectively analyzed, and the pathogenic factors of premature rupture of membranes, delivery method and general conditions of perinatal infants were analyzed. Results Vaginitis was a very com-mon cause of premature rupture of membranes, the incubation period of premature rupture of membranes was 2h-16d, (6.2± 1.3)d on average;and the difference in the A p-g a r score of perinatal infants between two delivery methods had no statis-tical significance by comparison (P>0.05); the differences in the incidence rate of complications of perinatal infants and death rate between the pregnant women whose pregnant weeks were between 28 weeks and 30 weeks and the pregnant women whose pregnant weeks were between 31 weeks and 34 weeks had statistical significance by comparison, (all P<0. 05). Conclusion We should timely treat the patients with preterm premature rupture of membrane complicated by premature delivery with the aid of expectant therapy, and the medical staff should timely give them moderate tocolytic, glucocorticoid and antibiotics to ensure the incubation period of pregnant women can be effectively prolonged to over 30 weeks thus effec-tively reducing the death rate of premature infants.%目的：探讨未足月(也即孕周处于28周与34周之间)胎膜早破并发早产的相关处理方法及其应用效果。方法整群选取回顾性分析该院门诊2012年3月—2014年12月收治的108例未足月妊娠胎膜早破并发早产的临床资料,分析其胎膜早破的发病因素、分娩方式以及围产儿的基本情况等。结果阴道炎是最为常见的胎膜早破的诱因；胎膜早破的潜伏期是2 h~16 d,平均是(6.2+1.3) d；两种分娩方式下,该组围产儿的A p-g a r评分相比,比较差异不具备统计学的意义(由于P>0.05)；针对孕周处于28周与30周的孕产妇和孕周处于31周与34周的孕产妇,这两组围产儿并发症的发生率和死亡率相比,比较差异有统计学的意义(由于P<0.05)。结论要及时地借助于期待疗法对未足月妊娠胎膜早破并发早产患者进行治疗,在孕产妇破膜后,医务人员要适时给予其适量的宫缩抑制剂、糖皮质激素和抗生素等药物,以使孕产妇的潜伏期能够有效延长到孕30周以上,从而可以有效地降低早产儿的死亡率。
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