首页> 中文期刊> 《中国继续医学教育》 >国外2型糖尿病治疗部分新药的临床研发动态

国外2型糖尿病治疗部分新药的临床研发动态

         

摘要

目的:探讨国外2型糖尿病治疗新药的研发的成果和治疗效果。方法选取我院自2012年3月~2013年3月收治的2型糖尿病患者124例作为研究对象,随机将其分成两组,即对照组患者62例采用胰高血糖素样肽-1(简称 GLP-1)受体激动剂进行治疗,观察组患者采用二肽基肽酶-4(简称 DPP-4)抑制剂治疗,对比两组患者的治疗效果。结果对照组患者的治疗有效率为46.77%,观察组患者的治疗总有效率为48.39%,两组数据对比差异不具有统计学意义,P >0.05。结论国外对于2性糖尿病治疗药物的研究明显迈进了新的台阶,其中GLP-1药物和 DPP-4药物在治疗的过程中均有非常好的效果。%Objective To investigate the results and treatment effect of foreign type 2 diabetes treatment for new drugs. Methods 124 cases of type 2 diabetic patients as the research objects were divided into two groups in our hospital from March 2012 March 2013, namely the control group 62 cases by glucagon like peptide-1 (GLP-1) receptor agonist treatment, the observation group were treated by dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment, compared two groups of patients with therapeutic effect. Results The effective rate of the control group was 46.77%, the total effective rate of the observation group was 48.39%, the difference of the two groups was not statistically significant, P>0.05. Conclusion Foreign for 2 diabetes therapeutics research obviously entered the new stage, which GLP-1 and DPP-4 drug in the course of treatment were by the very good effect.

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