疫苗对儿童甲型H1N1流感保护效果的病例对照研究

摘要

Objective To evaluate the preventive effect of trivalent inactivated influenza vaccine (TIV) for children H1N1 influenza. Methods Selected Children diagnosed of H1N1 flu as patient group, 1:1 matched healthy children as healthy control group, undiagnosed children H1N1 influenza as a negative control group, collected TIV vaccination information, tested sensitivity and statistical analysis. Results Children can play the best after TIV vaccination protective effect with 1 to 2 months. Conclusion Children should annually vaccinated early in the influenza epidemic of TIV.%目的：评价三价灭活流感疫苗（TIV）对儿童甲型H1N1流感保护效果。方法选择确诊儿童甲型H1N1流感患者作为病例组，1：1匹配选择健康儿童为健康对照组，选择未确诊儿童甲型H1N1流感患者作为阴性对照组。采集TIV接种信息，测试敏感度，统计分析。结果儿童接种TIV后1～2月内可以起到最佳保护作用。结论儿童应该每年在流感流行期前期接种TIV。