恶性肿瘤患者放化疗后真菌感染危险因素分析

摘要

Objective Nalysis of cancer patients after chemotherapy withfungal infection, distribution and induce risk factors. Methods Choose our hospital 386 cases of cancer patients, their specimens were analyzed with fungal culture, susceptibility testing. Results 386 cases of patient samples were tested in a fungal infection of 72, the infection rate was 18.65%(72/386), of which 55.5%for respiratory tract infections (40/72). Infect bacteria to yeast Candida albicans the most, accounting for 58.3%(42/72), followed by Candida tropicalis. Abuse of antibiotics, heavy use of hormones, invasive procedures are all risk factors for fungal infection. Conclusion Clinical treatment of cancer patients should be based on rational application of effective antifungal susceptibility test results to avoid misuse of antimicrobial drugs and hormones, effective prevention and control of fungal infections.%目的：分析探究恶性肿瘤患者放化疗后真菌感染的菌种、分布情况及诱发危险因素。方法选择我院收治的386例恶性肿瘤患者，对其标本进行真菌培养、药敏试验等分析研究。结果386例患者标本中共检查出真菌感染72株，感染率为18.65%（72/386），其中55.5%为呼吸道感染（40/72）；感染菌种以白色假丝酵母菌最多，占58.3%（42/72），其次是热带假丝酵母菌；滥用抗菌药物、大量使用激素、侵入性操作等都是真菌感染的危险因素。结论恶性肿瘤患者的临床治疗应根据药敏试验结果有效合理应用抗真菌药物，避免滥用抗菌药物和激素，有效预防和控制真菌感染。