老年严重肺栓塞临床特点及溶栓治疗分析

摘要

Objective To investigate the clinical characteristics of severe pulmonary embolism in elderly patients and the effect of different doses of thrombolytic therapy.Methods 80 elderly patients with severe pulmonary embolism in our hospital were selected and divided into the observation group and the control group according to the random number table method, 40 cases in each group, two groups were given the treatment of (injection with rt-PA) thrombolytic therapy, the observation group was treated with small dose, the control group was treated with large dose.Results The effective rate of observation group and control group were 85% and 82.5% respectively, and there was no significant difference between the observation group and the control group (P>0.05).ConclusionThe clinical characteristics of elderly patients with severe pulmonary embolism are varied and critical, and the thrombolytic therapy can achieve better results on the basis of low dose.%目的：探讨老年严重肺栓塞临床特点及不同剂量溶栓治疗的效果。方法选择我院收治的老年严重肺栓塞患者80例，根据随机数字表法分为观察组与对照组，各40例，两组都给予阿替普酶（注射用rt-PA）溶栓治疗，观察组采用小剂量治疗，对照组采用大剂量治疗。结果观察组与对照组的有效率分别为85.0%和82.5%，观察组的有效率与对照组对比，差异无统计学意义（P＞0.05）。结论老年严重肺栓塞临床特点多样且比较危重，在低剂量的基础上进行溶栓治疗能取得比较好的效果。