不同输血方法治疗自身免疫性溶血性贫血临床对比分析

摘要

目的：探讨不同输血方法治疗自身免疫性溶血性贫血患者的疗效。方法选取我院2013年10月～2015年10月收治的自身免疫性溶血性贫血患者92例，随机分为两组，每组各46例。对照组采用悬浮红细胞输注治疗，观察组采用洗涤红细胞输注联合血液置换治疗，对比两组输血前后血红蛋白、胆红素、红细胞、网织红细胞、治疗有效率和不良反应情况。结果观察组输血前后血红蛋白、胆红素、红细胞、网织红细胞改善幅度大于对照组，差异有统计学意义（P＜0.05）；观察组疗效高于对照组，差异有统计学意义（P＜0.05）；两组不良反应情况，差异无统计学意义（P＞0.05）。结论洗涤红细胞输注治疗自身免疫性溶血性贫血患者可提高疗效，改善临床症状，且安全性较高。%Objective To investigate the effect of different methods of blood transfusion in the treatment of autoimmune hemolytic anemia.Methods From October 2013 to October 2015, 92 cases of patients with autoimmune hemolytic anemia in our hospital were selected and divided into two groups, 46 cases in each group. Control group was given about infusion treatment of red blood cells suspension and observation group was given about wash red blood cell transfusion combined with blood exchange, To Compare the hemoglobin, bilirubin, red blood cell, reticulocyte, the curative efifciency and the adverse reaction rate before and after blood transfusion of the two groups. Results Improvement of hemoglobin, bilirubin, red blood cell, reticulocyte of observation group were larger than that of control group, the difference was statistically signiifcant (P<0.05). Clinical effect of observation group was better than control group, the difference was statistically signiifcant (P<0.05). There were no signiifcant difference about the rate of adverse reaction about two groups. (P>0.05).Conclusion Wash red blood cell transfusion in the treatment of patients with autoimmune hemolytic anemia has better effect and can improve clinical symptoms.