氯胺酮与硫喷妥钠复合麻醉对五指山小型猪麻醉效果的观察

摘要

To compared anesthetic effects of ketamine combined with thiopentalum natricum on Wuzhishan minipigs.40 healthy minipigs were divided into two groups: anesthesia by ketamine (n= 20,group 1) or ketamine combined with thiopentalum natricum (n=20,group 2).All minipigs underwent muscular or venous injection with these chemicals.It was found that anesthesia of group 2 maintained (198.0±32.7) min,anesthesia of groupl maintained (104.0±17.3) min,and group 2 showed better anaesthesia effect.Furthermore,the combined anesthetization could improve the anesthetic effect: increase muscular relaxation,do not interfere with respiration and cycle system,and show prolonged and more stable anesthesia with quick resuscitation.Thus,ketamine combined with thiopentalum natricum appears to be a perfect method for the prolonged surgery of experimental minipigs.%试验旨在比较氯胺酮与硫喷妥钠复合麻醉对五指山小型猪的麻醉效果.选取成年小型猪40头,分成氯胺酮组、氯胺酮与硫喷妥钠复合组两组,每组20头,采用肌肉注射和静脉注射麻醉.结果表明,氯胺酮组麻醉维持时间为(104.0士17.3)min,氯胺酮与硫喷妥钠复合组麻醉维持时间为(198.0士32.7)min,麻醉效果很好,提示复合麻醉能增强麻醉效果,提高肌肉松驰力,对呼吸、循环系统无明显的抑制,麻醉时间更长,更稳定,苏醒快.因此,氯胺酮与硫喷妥钠复合麻醉适合动物试验时间较长的手术,是一种较理想的小型猪麻醉剂.