采用液相还原的方法,以聚乙烯吡咯烷酮(PVP)为修饰剂,氯化铜为前驱体,水合肼为还原剂,成功制备了微米级Cu/PVP花状结构.采用扫描电子显微镜和X射线粉末衍射仪分析了所得样品的形貌与结构；利用差热分析测定了样品的热稳定性,并采用肉汤稀释法测试了其抗菌性能.结果表明,所制备的样品具有由多个Cu/PVP圆片组装而成的直径为6 μm的花状结构,其形貌依赖于反应条件.与此同时,花状结构的Cu/PVP对金黄色葡萄球菌和大肠杆菌具有明显的抗菌作用,相应的最小抑菌浓度(MIC)和最小杀菌浓度(MBC)分别为:41.25 mg/L、82.5 mg/L,以及20.63 mg/L、82.5 mg/L.与单一Cu纳米微粒相比,花状结构的Cu/PVP复合物的抗菌持久性明显较好.%Micrometer flower-like architectured copper/polyvinyl-pyrrolidones (Cu/PVPs) were successfully synthesized by liquid phase reduction with PVP as stabilizing agent, CuCl2 as precursor and hydrazine hydrate as reductant. The structure and morphology of as-synthesized samples were investigated by scanning electron microscopy and X-ray diffraction; and their thermal stability was evaluated by differential scanning calorimetric analysis. Moreover, the antibacterial performance of as-prepared samples against staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) was examined using broth dilution method. Results show that as-prepared flower-like Cu/PVPs consist of several intercrossing plates with an average diameter of 6 μm, and their morphology is dependent on the reaction condition. Besides, as-prepared Cu/ PVPs exhibit good antimicrobial activity against S. aureus and E. coli; and their minimum inhibitory concentration and minimum bactericidal concentration against the two kinds of bacteria are 41.25 mg/L and 82.5 mg/L, as well as 20.63 mg/L and 82.5 mg/L, respectively. Moreover, as compared with Cu nanoparticles, Cu/PVP architectures present better lasting antimicrobial activity.
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