采用强酸性离子交换树脂、环己烷分别替代传统的催化剂硫酸及带水剂苯,以2-丁烯-1,4-二醇和正丁醛为原料,制备了2-正丙基-4,7-二氢-1,3-二氧七环,研究了收率的各种影响因素.改进后的工艺革除了高毒性苯,正丁醛与2-丁烯-1,4-二醇最佳投料比为1.2∶1(摩尔比),收率达95％以上,催化剂可循环使用5次.本工艺后处理简单,适于工业化应用.%In stead of traditional sulfuric acid catalyst and benzene as water-carrying agent,strongly acidic ion exchange resin and cyclohexane were applied to the preparation of 4,7-dihydro-2-n-propyl-l ,3-dioxetpin from 2-butane-1 ,4-diol and butyraldehyde, and the factors affecting the yield were studied. After high toxic benzene removed, the optimum molar ratio of butyraldehyde to 2-butane-l ,4-diol is 1. 2 : 1, the yield is above 95% ,and the catalyst can be recycled 5 times. The post treatment of this process is simple,so it is suitable for industrial application.
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