呼吸机早期干预对吸入性损伤治疗结果的影响

摘要

Sixty patients with inhalation injury were analyzed retrospectively in our ward from January 2005 to January 2010. According to the time of receiving life-support machine after hospitalization the 60 patients were divided into two groups. Group A is from Jaunary 2005 to December 2007,total 25. Group B is from Jaunary 2008 to December 2010,total 35. For the patients of group A their time of receiving life-support machine in the treatment is later than those of group B( P <0.05 ). Group A received life-support machine( 25. 92 ± 6. 47 )h after injury,group B received life-support machine( 15.77 ±5.24 )h after injury. Start time of receiving life-support machine in the treatment , corrected effects of hypoxemia, VAP and mortality, length of stay in hospital were comparatively analyzed. Results After treatment, there are differences in 48 hours PaO2 , VAP incidence, mortality and length of stay( P < 0. 05 ). Conclusion The effect of life-support machine use in patients with inhalation injury in early period is satisfactory, VAP and mortality incidence decreased, the time of curing inhalation injury shortened.%目的 探讨吸入性损伤病人早期使用呼吸机对吸入性损伤病人治疗结果的影响.方法 回顾性分析2005年1月至2010年1月收治的吸入性损伤病人60例,按照入院后使用呼吸机进行干预治疗起始时间的差异分为两组,A组为2005～2007年入院患者,共25例,B组为2008～2010年入院的患者,共有35例.其中A组患者接受呼吸机治疗的起始时间较B组患者晚(P<0.05),A组接受呼吸机治疗的时间为伤后(25.92±6.47)h,B组接受呼吸机治疗的时间为伤后(15.77±5.24)h.根据两组患者接受呼吸机治疗的起始时间上的差异,对低氧血症纠正效果、VAP发生率、死亡率、住院时间进行比较分析.结果 两组患者经过治疗后,48 h PaO2、VAP发生率和死亡率及住院时间均存在差异(P<0.05).结论 早期应用呼吸机通气治疗吸入性损伤治疗效果满意,VAP发生率及死亡率降低,缩短吸入性损伤治疗时间.