骨疏灵颗粒提取工艺优化

摘要

目的 优选中药复方制剂骨疏灵的提取工艺.方法采用正交试验设计,以淫羊藿苷和黄芪甲苷的提取率为评定指标,用多指标综合评分法进行数据处理,优化提取条件.结果 优选出的提取条件为煎煮2次,每次1 h,第1次加水量为11倍,第2次加水量为8倍.结论优选得到的工艺稳定可行.%Objective To optimize extraction technology of Gushuling,a compound preparation of Chinese medicine. Methods Orthogonal design was used to evaluate the icariin with astragaloside Ⅳ extraction rate as indexes. Data processing was carried out with comprehensive evaluation method for optimizing the extraction condition. Results Optimized extraction conditions were as follows: the drugs were decocted twice and 1h per time;at first water was added to 11 times and for the second time the amount of water was 8 times. Conclusion The optimized technology is stable and feasible.