支气管动脉栓塞介入治疗肺结核合并糖尿病大咯血的疗效与安全性分析

摘要

目的 研究介入治疗对肺结核合并糖尿病患者大咯血的临床效果与安全性.方法 采用数字随机表法将85例肺结核合并糖尿病患者随机分为对照组(45例)与观察组(40例),所有患者均出现大咯血症状,对照组给予控制血糖+抗结核+内科用药控制咯血,观察组给予控制血糖+抗结核+支气管动脉栓塞术介入治疗控制咯血,比较两组治疗效果、症状改善及不良反应.结果 观察组治疗总有效率显著高于对照组(P<0.01),两组治疗第3、5、7天后的咯血量均明显减少,但观察组降低幅度相比对照组更为显著(P<0.01),且不良反应发生率明显少于对照组(P<0.01).结论 采用支气管动脉栓塞术介入治疗肺结核合并糖尿病患者大咯血的临床效果确切,能有效控制患者的咯血症状,减少咯血量,同时无严重不良反应发生,安全可靠,值得临床推荐应用.%Objective To investigate the clinical efficacy and safety of interventional therapy for massive hemoptysis in patients with pulmonary tuberculosis complicated with diabetes mellitus.Methods 85 patients with pulmonary tuberculosis complicated with diabe-tes were randomly divided into the control group(45 cases)and observation group(40 cases).All patients had symptoms of hemopty-sis.The control group was given control of blood glucose +anti-tuberculosis medicine drug and the observation group was given glucose control +anti-tuberculosis control +bronchial artery embolization interventional therapy to control hemoptysis.The symptoms and ad-verse reactions of the two groups were compared.Results The total efficiency of the observation group was significantly higher than the control group(P<0.01).After 3 d,5 d and 7 d,hemoptysis were found in the treatment groups,while the observation group decreased significantly than the control group(P<0.01),and the incidence of adverse events was less than the control group(P<0.01).Con-clusions The clinical effect of bronchial artery embolization in interventional treatment of hemoptysis of pulmonary tuberculosis com -plicated with diabetes which can effectively control the symptoms of hemoptysis patients,reduce the amount of hemoptysis is effective, safe,reliable,with no serious adverse reactions,and worthy of clinical reference.