放置宫内节育器后出现月经过多临床治疗措施探讨

摘要

Objective To compare three kinds of pharmacotherapies as treatment to menorrhagia after placing the intrauterine device, and to discuss clinical curative effects of the three kinds of medicine and analyse their differences. Methods A total of 174 patients treated at our station for menorrhagia after the intrauterine device was placed from March 2010 to March 2012 were chosen as study objectives, and divided into three groups randomly: group A, B, C, with 58 patients in each group. Ibuprofen was administered to group A as treatment, tranexamic acid to group B as treatment, and Gongxuening capsule to group C as treatment. The hemoglobin content, menstrual quantity and adverse reactions after drugs being taken before and after treatment were observed. Results Hemoglobin content in group A and C rose( P < 0.05 ), but that in group B had no evident changes( P > 0. 05 ); hemoglobin content in group A increased rapidly and had statistical difference compared with group C( P<0.05 ); all these patients'menstrual quantity decreased( P<0.05 ),the decreasing degree of menstrual quantity in group B was the most obvious and its smooth time was the shortest; the decreasing degree of menstrual quantity in group C was the slowest one and its smooth time was the longest, there was obvious differences between these two groups and their differences had statistical significance( P <0. 05 );the digestive symptoms were relatively serious among the untoward effects. The untoward effect types and cases in Group A were the most, while those in Group C were the least. Conclusion All three pharmacotherapies have evident treatment effects to menorrhagia after the intrauterine device is placed, but they have their own features, and in the clinical application, we should use medicines according to patients'actual conditions.%目的 探讨布洛芬、氨甲环酸及宫血宁胶囊3种药物对放置宫内节育器后出现月经过多的临床疗效及其相互间的差异.方法 选取2010年3月至2012年3月我站收治的因放置宫内节育器后出现月经过多的患者174例,将其随机分为A、B、C 3组,每组均为58例.A组应用布洛芬;B组应用氨甲环酸;C组应用宫血宁胶囊治疗,观察3组治疗前后血红蛋白含量、月经量和不良反应.结果 A和C组患者血红蛋白含量均上升(P<0.05),B组血红蛋白含量与治疗前比,差异无统计学意义(P>0.05),A组血红蛋白含量上升迅速,与C组相比差异有统计学意义(P<0.05).3组患者月经量均有下降,B组月经量下降程度最为明显,平稳时间最短,C组下降程度最慢,平稳时间最长,两者比较差异有统计学意义(P<0.05).不良反应以消化道症状相对严重,A组不良反应类型和例数最多,C组不良反应最少.结论 3种药物对放置宫内节育器后出现的月经过多均有明显治疗效果,但3种药的治疗效果各有其特点,临床应用中应结合患者实际情况选择用药.