Objective To provide the relationship between pregnancy outcome and relevant perinatal factors of macrosomia born by primiparous women. Methods The clinical data of 529 macrosomia fetuses,and 529 pregnant women who delivered mature and natural fetus as the control group were reviewed and analyzed. Results The stature,body weight during the third trimester of pregnancy,late pregnancy uterine height,abdominal circumference,fetal abdominal circumference,fetal femur length in macrosomia born by primiparous women group were significantly higher than those in normal weight infants born by primiparous women( P < 0. 05). The incidence of abnormal stages of la-bor,perineal or cervical lacerations,postpartum hemorrhage,neonatal asphyxia in macrosomia born by primiparous women group were signifi-cantly higher than those in normal weight infants born by primiparous women( P < 0. 05). There was no significant differences in gestational age,gestational weeks,biparietal diameter,gravidity,selective cesarean section rate between the two groups(P > 0. 05). Conclusion En-hancing perinatal management of primiparous women,choosing appropriate delivery modes are important for reducing maternal - infantile complications.%目的：研究初产妇分娩巨大儿的相关围产因素与分娩方式的关系。方法回顾性分析2014年1月至12月在安徽省妇幼保健院分娩的529例无内外科合并症的分娩巨大儿的初产妇临床资料，并与529例同期随机选择的无合并症分娩正常体质量儿的初产妇进行比较。结果初产巨大儿母亲的身高、体质量（孕前体质量及分娩前体质量）、宫高、腹围、B 超测量的胎儿腹围、胎儿股骨长度均高于初产妇正常体质量儿组（ P <0.05）。初产巨大儿孕妇出现头盆不称、持续性枕横位或枕后位、子宫收缩乏力、会阴裂伤（Ⅲ度及以上）、胎儿窘迫、产后出血及新生儿窒息率高于初产妇正常体质量儿组（ P <0.05）。而初产妇巨大儿组的年龄、孕周、孕次、胎儿双顶径和择期剖宫产（未经阴道试产）率与正常体质量儿组比较差异无统计学意义（ P >0.05）。结论做好初产妇孕期饮食指导，加强围生期管理，预防巨大儿的同时，提高产前预测巨大儿准确率，选择适当的分娩方式对降低母婴并发症至关重要。
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