心脏自主神经重构与心肌梗死后室性心律失常

摘要

心肌梗死后心脏不同区域出现不同程度的去迷走神经支配、去交感神经支配以及交感神经过度再生.这种心脏自主神经的不均一重构加重了心肌梗死后心肌的电生理异质性,导致了室性心律失常易感性增加.多种针对自主神经重构的治疗手段可以有效预防及治疗心肌梗死后患者的室性心律失常,具有较大的临床应用前景.%The coexistence of denervation and hyperinnervation after myocardial infarction can increase electrophysiological heterogeneity, leading to ventricular arrhythmias. Therapies that modulate autonomic neural remodeling can prevent ventricular arrhythmia in patients prior with myocardial infarction and may have clinical value.