内脏脂肪素与胰岛素抵抗和动脉粥样硬化的研究进展

摘要

Visfatin, a newly identified adipocytokine, is mainly expressed in visceral adipose tissue. With Nampt enzymatic activity, visfatin is related to inflammation, endothelial dysfunction, angiogenesis, vulnerable plaque, anti-cell senescence or apoptosis or ischemia-reperfusion myocardial protection, may play an important role in the progress of glycometabolism or atherosclerosis diseases.%内脏脂肪素是近年来发现的主要由内脏脂肪组织表达的一种新型脂肪细胞因子,具有Nampt酶活性,与炎症、内皮功能障碍、血管增生、易损斑块、抗细胞衰老及凋亡、缺血再灌注心肌保护等相关,可能在糖代谢和动脉粥样硬化疾病发生发展中具有重要的作用.