目的：利用Solaris 10操作系统中自带的Perl程序创建具有自适应性质的动态脚本,实现调强放射治疗( IMRT)计划设计的自动执行,并研究其在计划设计中的应用前景。方法选取6例食管癌患者,利用Perl程序创建动态脚本,通过脚本回放,实现IMRT放疗计划的设计,并利用体积剂量,计划完成时间等参数与人工设计的计划进行对比。结果在不明显改变计划质量的前提下,脚本计划时间(12．70±1．47)min相比人工计划时间(27．72±2．29) min平均缩短15 min,差异有统计学意义(P<0．05)。结论利用Perl程序创建动态脚本能够自适应靶区与剂量,通过脚本回放可快速完成IMRT计划的设计。%Objective Underwent adaptive dynamic scripts based on the Perl program of Solaris 10 operating sys-tem and scripting playback of pinnacle system which automatically performed the plan of intensity modulated radio-therapy and analyzed the dose distribution produced by the dynamic scripts, and then explored them in the treat-ment plan of intensity modulated radiotherapy. Methods Six patients with esophageal carcinoma received radiother-apy were selected. Two IMRT plans for each patient were designed: the artificial plan and the plan based on the dynamic scripts through playback function. The dose volume histogram, plan completion time, and other parame-ters were compared respectively. Results The average time of IMRT plan(12. 70 ± 1. 47) minutes achieved by the application of dynamic scripts was 15 minutes shorter than that of the artificial plan(27. 72 ± 2. 29) minutes, and the difference was statistically significant ( P<0. 05 ) . Conclusion The dynamic scripts based on the Perl program can adapt the targets and dose, and can quickly fulfill the IMRT plan through playback function.
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