放疗并用胞必佳治疗肺癌29例疗效观察

摘要

Twenty-nine patients with lung cancer were treated with radiotherapy in combination with Nocardia rubra cell wall skeleton (N-CWS). Another 29 cases of lung cancer only received radiotherapy. In the N-CWS group，7 patients obtained complete remission (CR) and 17 partial remission with the effective rate being (82.7 %)，while in the control group，3 patients obtained CR and 14 PR with the effective rate being 58.6 %. There was a statistical difference between the N-CWS group and control group (P<0.05). In the N-CWS group，fever occurred in 34.5 % and skin reaction in 55.1 %. Both of them were grade I mainly. In conclusion，N-CWS could improve short-term effects of radiotherapy in the treatment of lung cancer with a tolerable toxicity reaction.%29例肺癌行放疗联合红色诺卡氏菌细胞壁骨架（胞必佳）治疗，另外29例行单纯放疗。胞必佳组获完全缓解（CR）7例、部分缓解（PR）17例，有效率82.7%；对照组获CR 3例、PR 14例，有效率58.6%。两组有效率统计学比较有差异（P<0.05）。胞必佳组发热发生率34.5%，皮肤反应发生率55.1%，二者均以Ⅰ度为主。认为胞必佳可提高肺癌单纯放疗的近期疗效，毒副反应轻。